It's an ordinary day for Tom Baldwin, that is until Diana shows up at his house to arrest him for murder. It seems that earlier that morning Tom entered an NTAC interrogation room and shot T.J. Kim (the Nova member arrested in "A New World"). Several witnesses can even place him at the scene.
The problem is that Tom hasn't been in to work yet and has no recollection of anything Diana is talking about. Unwilling to turn himself in, Tom goes on the run and becomes a fugitive in order to get to the truth.

It's eventually discovered that a teenage 4400 named Boyd Gelder, recruited by Nova, was sent to kill T.J. Kim before she could compromise the organization. Gelder's ability allows him to make people perceive him to be any identity he chooses. In the end, Boyd Gelder is apprehended and Tom is able to clear his name.

At the 4400 Center, Shawn helps Isabelle catch up on some of the milestones she missed growing from an infant to a woman overnight: learning to drive, swim, etc. But Shawn soon learns that Isabelle's list includes losing her virginity to him. Shawn is hesitant since he promised Richard that he would be a friend and only a friend to his daughter. But in the end, Shawn gives in to temptation.

Meanwhile, Richard undertakes a journey to release Lily's ashes, and Diana discovers that Kevin Burkhoff, who has been injecting himself with doses of promicin, has developed a 4400 ability.